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Journal » What’s the difference between PRP and PRF?
Platelet Rich Plasma and Platelet Rich Fibrin are both injectable skin rejuvenation treatments & both follow the same process. Both treatments are effective in stimulating collagen, elastin and new skin cell production and are effective in the treatment of fine lines, wrinkles, skin texture and fading dark spots. Both are used on the scalp to stimulate hair growth.
The difference between these treatments lies in how your blood is collected and prepared. Both processes require taking a blood sample, spinning the sample in a centrifuge, and reinjecting either the plasma (PRP) or fibrin (PRF) into the skin. Because both PRP and PRF use your own blood, both treatments are extremely safe with a very low chance of having an adverse reaction. By harnessing the body’s own restorative powers, we are able to achieve transformative and natural-looking results.
Platelet Rich Plasma (PRP) is the traditional platelet treatment. The blood sample is spun at a high speed in the centrifuge, this pushes the red blood cells to the bottom of the container and separates the plasma. The PRP sample is added to a vial containing anticoagulants to prevent the blood from clotting during the injections.
Plasma is a concentration of platelet cells which are critical for blood clotting, cell multiplication and specialisation required for healing soft tissue and bone. These characteristics of plasma are ideal for skin rejuvenation. PRP is known to improve tissue repair and increases collagen production, it is powerfully effective in the treatment of skin damage and reduces the appearance of fine lines and wrinkles. PRP is most effective if you have uneven skin tone, hyperpigmentation, acne scars or fine lines and wrinkles.
Platelet Rich Fibrin (PRF) is spun at a lower speed so that some of the white blood cells, stem cells and fibrin remain in the platelet layer. This mixture contains approximately 10 times the platelet concentration that is found within the body, unlike PRP which contains 2-5 times the concentration. In spinning the blood at a lower rate there is less trauma to the individual cells and the addition of stem cells to the fibrin also means there are more healing factors within the PRF mixture than is typically seen in PRP.
PRF is effective in the same areas as PRP, but PRF is more effective on deep wrinkles or more advanced signs of ageing because PRF is achieved with a simplified preparation with no addition of an anticoagulant, unlike PRP. This creates a spongy texture that allows the effects of PRF to last up to a week – offering long-lasting results. Because of this texture, PRF is often used as a filler, building volume in the skin.
Both PRP and PRF are industry-leading treatments for skin rejuvenation and hair loss. Please note that if you have a blood or bleeding disorder, or you’re on anti-clotting or blood-thinning medications, you are not a good candidate for PRP or PRF treatments. If you have further questions about these treatments, we recommend contacting our team on 0118 334 7879 or booking a consultation to discuss with our Aesthetics Practitioners.
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